The Combipack from Porvair Sciences has been introduced for laboratories tasked with protein precipitation sample preparation. Comprising five colour-coded Porvair P3 protein precipitation plates and five 1 ml deep well collection plates, the Combipack contains all the elements required to accelerates the traditionally troublesome procedure at a budget price.
Biological samples commonly contain proteins that interfere with downstream applications. The P3 protein precipitation plate uses the crash method, in which the protein is denatured with acetronitrile and the flocculant filtered out, allowing 96 samples to be handled at one time. The P3 is based on the industry standard MicroLute format but without the chromatographic sorbent.
Protein crashes out of solution and precipitates directly in each well when acetonitrile is added, thus solving all common problems associated with the crash technique of protein clean-up. The dual frit, hydrophobically treated matrix means that there is no wetting out and leakage of the sample through the plate before the application of vacuum.
The P3 is now commonly used as the protein precipitation plate of choice by many major pharmaceutical companies. Optional drain cap and top cap mats are available for those wishing to use vortex sample mixing.
Manufactured to the standard ANSI/SBS 96-well format footprint, all plates in the Combipack are fully automation compatible.
Porvair Sciences Ltd, +44 1978 666240, int.sales@porvair-sciences.com, www.porvair-sciences.com.