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Alzheimer's

Janssen Pharmaceuticals is set to work with health technology company Medopad on a project to develop a digital biomarker for Alzheimer’s disease. Read more

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In a surprise announcement, pharma company Biogen has revealed it is set to pursue FDA approval for its Alzheimer’s drug aducanumab, which was previously discontinued in March earlier this year. Read more

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A new blood test could help doctors identify people who are likely to develop Alzheimer’s disease up to 20 years before the condition occurs. Read more

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Robert Hohler, owner of Companions of London, writes about whether a new alzheimer's vaccine could help treat dementia. Read more

Opinion

Scientists at the University of Waterloo have discovered that antidepressant medications can be used to treat Alzheimer’s disease. Read more

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According to a recent study from the University of Eastern Finland, there is a modestly increased risk of Alzheimer’s disease associated with the use of benzodiazepines and related drugs (Z drugs). Read more

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BIOCRATES has reported the latest breakthrough in Alzheimer’s research from the Alzheimer’s Disease Metabolomics Consortium (ADMC), connecting how gut bacteria and lipid metabolism influences the disease Read more

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Positive topline results from the Phase II clinical study assessing an anti-amyloid beta protofibril antibody in patients with early Alzheimer’s disease have been revealed by Eisai and Biogen. Read more

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An option exercise to further reduce the royalty rates payable on potential future sales of aducanumab — a Phase III investigational treatment for early Alzheimer’s disease — has been announced by Biogen and Neurimmune. Read more

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According to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE, antiepileptic drugs are associated with an increased risk of Alzheimer’s disease and dementia. Read more

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After the successful completion of the Phase I trial, Araclon Biotech and TFS International have announced a continuation of their partnership to advance the trial of the Alzheimer’s disease (AD) vaccine ABvac40 into Phase II. Read more

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A drug that was believed to be a promising new therapeutic option for suffers of Alzheimer’s (idalopirdine) — from the Danish pharma company, Lundbeck — has failed to show clinical benefit in three randomised trials. Read more

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A clinical study, performed by researchers from the UK and China, has demonstrated that novel triple receptor agonists (TAs) originally developed to treat Type 2 diabetes, significantly reversed memory loss in a mouse model of Alzheimer’s disease. Read more

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Axovant Sciences, a clinical-stage biopharmaceutical company, has revealed negative topline results of its Phase III MINDSET trial in Alzheimer’s disease, but the CEO has stressed that the company will continue advancing its pipeline Read more

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A recent study from the University of Eastern Finland has demonstrated that proton pump inhibitors, commonly used as antiulcer drugs in older patients, do not increase the risk of Alzheimer’s disease. Read more

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Professor Giovanna Mallucci and her team have identified two drugs that can block the death of brain cells in mice models of neurodegeneration. This research builds on the earlier breakthrough by the team four years ago. Read more

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Results from studies of ALZ-801 and its active molecule tramiprosate support the study design for the clinical programme, reports Alzheon. Read more

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According to business intelligence provider GBI Research, pharmaceuticals company Roche will be the biggest mover in the neurodegenerative drugs space over the next five years. Read more

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A recent study from the University of Eastern Finland has shown that the use of benzodiazepines and similar drugs was associated with a 20% increased risk of stroke for patients with Alzheimer’s disease. Read more

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A supercharged version of the acid derived from our Christmas dinner veg is the basis of new research aimed at developing a new drug to treat Alzheimer’s disease. Read more

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