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Thu, 10 Jun 2021 09:52:02 -0000 Reece Armstrong The FDA has approved Biogen’s Alzheimer’s drug Aduhelm making it the first new treatment for the disease to come to market since 2003. https://www.epmmagazine.com/pharma-manufacturing-news/new-drug-development-approvals-regulatory-news/fda-approves-controversial-alzheimer-s-drug-from-biogen/ https://www.epmmagazine.com/pharma-manufacturing-news/new-drug-development-approvals-regulatory-news/fda-approves-controversial-alzheimer-s-drug-from-biogen/ Thu, 10 Jun 2021 09:52:02 -0000 Alzheimers.png Speciality chemicals provider Evonik has entered into a supply agreement with the biotechnology company Cassava Sciences. https://www.epmmagazine.com/pharma-manufacturing-news/new-drug-development-approvals-regulatory-news/evonik-to-supply/ https://www.epmmagazine.com/pharma-manufacturing-news/new-drug-development-approvals-regulatory-news/evonik-to-supply/ Tue, 09 Mar 2021 14:29:07 -0000 Alzheimer's Researchers in the UK and Australia have identified a new biomarker which could support the development of new treatments for dementia. https://www.epmmagazine.com/pharma-manufacturing-news/researchers-identify-biomarker-which-could-help/ https://www.epmmagazine.com/pharma-manufacturing-news/researchers-identify-biomarker-which-could-help/ Mon, 27 Jul 2020 09:05:00 -0000 Dementia A possible vaccine for dementia is one-step closer to clinical trials after promising research in mice. https://www.epmmagazine.com/pharma-manufacturing-news/possible-dementia-vaccine-targets-clinical-trials/ https://www.epmmagazine.com/pharma-manufacturing-news/possible-dementia-vaccine-targets-clinical-trials/ Thu, 02 Jan 2020 11:00:00 -0000 Dementia Janssen Pharmaceuticals is set to work with health technology company Medopad on a project to develop a digital biomarker for Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/janssen-to-work-with-medopad-on-developing-digital-test-for-/ https://www.epmmagazine.com/pharma-manufacturing-news/janssen-to-work-with-medopad-on-developing-digital-test-for-/ Tue, 12 Nov 2019 11:10:00 -0000 Alzheimer's In a surprise announcement, pharma company Biogen has revealed it is set to pursue FDA approval for its Alzheimer’s drug aducanumab, which was previously discontinued in March earlier this year. https://www.epmmagazine.com/pharma-manufacturing-news/biogen-target-alzheimer-s-drug/ https://www.epmmagazine.com/pharma-manufacturing-news/biogen-target-alzheimer-s-drug/ Wed, 23 Oct 2019 10:30:00 -0000 Alzheimer's A new blood test could help doctors identify people who are likely to develop Alzheimer’s disease up to 20 years before the condition occurs. https://www.epmmagazine.com/pharma-manufacturing-news/new-blood-test-could-help-detect-alzheimer-s-earlier/ https://www.epmmagazine.com/pharma-manufacturing-news/new-blood-test-could-help-detect-alzheimer-s-earlier/ Mon, 05 Aug 2019 09:05:00 -0000 blood test Robert Hohler Robert Hohler, owner of Companions of London, writes about whether a new alzheimer's vaccine could help treat dementia. https://www.epmmagazine.com/pharmaceutical-industry-insights/could-this-alzheimer-s-vaccine-cut-dementia-cases-in-half/ https://www.epmmagazine.com/pharmaceutical-industry-insights/could-this-alzheimer-s-vaccine-cut-dementia-cases-in-half/ Tue, 22 Jan 2019 09:55:00 -0000 Alzheimer's Scientists at the University of Waterloo have discovered that antidepressant medications can be used to treat Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/antidepressants-can-treat-alzheimer-s-scientists-discover/ https://www.epmmagazine.com/pharma-manufacturing-news/antidepressants-can-treat-alzheimer-s-scientists-discover/ Thu, 11 Oct 2018 13:28:00 -0000 alzheimers.jpg According to a recent study from the University of Eastern Finland, there is a modestly increased risk of Alzheimer’s disease associated with the use of benzodiazepines and related drugs (Z drugs). https://www.epmmagazine.com/pharma-manufacturing-news/risk-of-alzheimers-linked-with-benzodiazepines/ https://www.epmmagazine.com/pharma-manufacturing-news/risk-of-alzheimers-linked-with-benzodiazepines/ Wed, 15 Aug 2018 11:48:44 -0000 brain BIOCRATES has reported the latest breakthrough in Alzheimer’s research from the Alzheimer’s Disease Metabolomics Consortium (ADMC), connecting how gut bacteria and lipid metabolism influences the disease https://www.epmmagazine.com/pharma-manufacturing-news/latest-breakthrough-in-alzheimers-research-announced/ https://www.epmmagazine.com/pharma-manufacturing-news/latest-breakthrough-in-alzheimers-research-announced/ Fri, 27 Jul 2018 11:47:55 -0000 Alzheimer's Positive topline results from the Phase II clinical study assessing an anti-amyloid beta protofibril antibody in patients with early Alzheimer’s disease have been revealed by Eisai and Biogen. https://www.epmmagazine.com/pharma-manufacturing-news/positive-topline-results-in-study-for-alzheimers-treatment/ https://www.epmmagazine.com/pharma-manufacturing-news/positive-topline-results-in-study-for-alzheimers-treatment/ Mon, 09 Jul 2018 12:47:46 -0000 Alzheimer's An option exercise to further reduce the royalty rates payable on potential future sales of aducanumab — a Phase III investigational treatment for early Alzheimer’s disease — has been announced by Biogen and Neurimmune. https://www.epmmagazine.com/pharma-manufacturing-news/transaction-to-reduce-royalty-rates-on-alzheimers-drug/ https://www.epmmagazine.com/pharma-manufacturing-news/transaction-to-reduce-royalty-rates-on-alzheimers-drug/ Wed, 02 May 2018 09:17:44 -0000 Alzheimer's According to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE, antiepileptic drugs are associated with an increased risk of Alzheimer’s disease and dementia. https://www.epmmagazine.com/pharma-manufacturing-news/antiepileptic-drugs-linked-with-alzheimers-dementia/ https://www.epmmagazine.com/pharma-manufacturing-news/antiepileptic-drugs-linked-with-alzheimers-dementia/ Mon, 09 Apr 2018 12:45:50 -0000 Epilepsy drugs After the successful completion of the Phase I trial, Araclon Biotech and TFS International have announced a continuation of their partnership to advance the trial of the Alzheimer’s disease (AD) vaccine ABvac40 into Phase II. https://www.epmmagazine.com/pharma-manufacturing-news/araclon-tfs-to-continue-partnership-advancing-alzheimer%E2%80%99s-va/ https://www.epmmagazine.com/pharma-manufacturing-news/araclon-tfs-to-continue-partnership-advancing-alzheimer%E2%80%99s-va/ Fri, 26 Jan 2018 12:37:21 -0000 Alzheimer's Felicity Thomas A drug that was believed to be a promising new therapeutic option for suffers of Alzheimer’s (idalopirdine) — from the Danish pharma company, Lundbeck — has failed to show clinical benefit in three randomised trials. https://www.epmmagazine.com/pharma-manufacturing-news/alzheimer%E2%80%99s-research-suffers-again-as-promising-drug-shows-n/ https://www.epmmagazine.com/pharma-manufacturing-news/alzheimer%E2%80%99s-research-suffers-again-as-promising-drug-shows-n/ Thu, 11 Jan 2018 12:41:01 -0000 Alzheimers A clinical study, performed by researchers from the UK and China, has demonstrated that novel triple receptor agonists (TAs) originally developed to treat Type 2 diabetes, significantly reversed memory loss in a mouse model of Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/diabetes-drugs-offer-hope-in-the-fight-against-alzheimer%E2%80%99s-d/ https://www.epmmagazine.com/pharma-manufacturing-news/diabetes-drugs-offer-hope-in-the-fight-against-alzheimer%E2%80%99s-d/ Tue, 02 Jan 2018 15:42:57 -0000 Alzheimer's Axovant Sciences, a clinical-stage biopharmaceutical company, has revealed negative topline results of its Phase III MINDSET trial in Alzheimer’s disease, but the CEO has stressed that the company will continue advancing its pipeline https://www.epmmagazine.com/pharma-manufacturing-news/clinical-setback-with-alzheimer-drug-will-not-deter-axovant-/ https://www.epmmagazine.com/pharma-manufacturing-news/clinical-setback-with-alzheimer-drug-will-not-deter-axovant-/ Thu, 28 Sep 2017 11:13:36 -0000 Alzheimer's A recent study from the University of Eastern Finland has demonstrated that proton pump inhibitors, commonly used as antiulcer drugs in older patients, do not increase the risk of Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/proton-pump-inhibitors-do-not-increase-alzheimer%E2%80%99s-risk-note/ https://www.epmmagazine.com/pharma-manufacturing-news/proton-pump-inhibitors-do-not-increase-alzheimer%E2%80%99s-risk-note/ Mon, 07 Aug 2017 12:41:07 -0000 Alzheimers Felicity Thomas Professor Giovanna Mallucci and her team have identified two drugs that can block the death of brain cells in mice models of neurodegeneration. This research builds on the earlier breakthrough by the team four years ago. https://www.epmmagazine.com/pharma-manufacturing-news/liquorice-and-antidepressant-could-save-brain-cells/ https://www.epmmagazine.com/pharma-manufacturing-news/liquorice-and-antidepressant-could-save-brain-cells/ Thu, 20 Apr 2017 10:11:04 -0000 Liquorice Felicity Thomas Results from studies of ALZ-801 and its active molecule tramiprosate support the study design for the clinical programme, reports Alzheon. https://www.epmmagazine.com/pharma-manufacturing-news/data-supports-study-design-for-alz-801-clinical-programme/ https://www.epmmagazine.com/pharma-manufacturing-news/data-supports-study-design-for-alz-801-clinical-programme/ Fri, 31 Mar 2017 10:03:31 -0000 Alzheimer's According to business intelligence provider GBI Research, pharmaceuticals company Roche will be the biggest mover in the neurodegenerative drugs space over the next five years. https://www.epmmagazine.com/pharma-manufacturing-news/roche-to-gain-most-ground-in-neurodegnerative-drugs-market-b/ https://www.epmmagazine.com/pharma-manufacturing-news/roche-to-gain-most-ground-in-neurodegnerative-drugs-market-b/ Tue, 14 Feb 2017 14:15:00 -0000 Market Share A recent study from the University of Eastern Finland has shown that the use of benzodiazepines and similar drugs was associated with a 20% increased risk of stroke for patients with Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/benzodiazepines-found-to-increase-risk-of-stroke-among-peopl/ https://www.epmmagazine.com/pharma-manufacturing-news/benzodiazepines-found-to-increase-risk-of-stroke-among-peopl/ Mon, 16 Jan 2017 11:35:00 -0000 Alzheimer's A supercharged version of the acid derived from our Christmas dinner veg is the basis of new research aimed at developing a new drug to treat Alzheimer’s disease. https://www.epmmagazine.com/pharma-manufacturing-news/eat-your-sprouts-supercharged-brussel-sprout-vitamin-inspira/ https://www.epmmagazine.com/pharma-manufacturing-news/eat-your-sprouts-supercharged-brussel-sprout-vitamin-inspira/ Fri, 23 Dec 2016 12:15:00 -0000 Brussel Sprouts Global healthcare company Lilly has announced the results of a phase 3 clinical trial, designed to test the efficacy of a drug to slow the effects of Alzheimer’s. https://www.epmmagazine.com/pharma-manufacturing-news/promising-alzheimers-drug-shows-no-effect-on-the-disease/ https://www.epmmagazine.com/pharma-manufacturing-news/promising-alzheimers-drug-shows-no-effect-on-the-disease/ Thu, 24 Nov 2016 15:10:00 -0000 Alzheimer's Biopharmaceutical company PhoreMost has entered into a research collaboration with the laboratory of Professor David Rubinsztein at the University of Cambridge. https://www.epmmagazine.com/pharma-manufacturing-news/the-undruggables/ https://www.epmmagazine.com/pharma-manufacturing-news/the-undruggables/ Tue, 18 Oct 2016 09:50:00 -0000 Neurodegeneration Biopharmaceutical company Probiodrug AG have announced the first results of a preclinical combination trial targeting pGlu-Abeta, a peptide thought to play a role in Alzheimer’s disease progression. https://www.epmmagazine.com/pharma-manufacturing-news/combination-therapy-shows-promising-results-in-alzheimer-s-p/ https://www.epmmagazine.com/pharma-manufacturing-news/combination-therapy-shows-promising-results-in-alzheimer-s-p/ Wed, 14 Sep 2016 10:30:00 -0000 Alzheimers EPM Lu Rahman A clinical trial of a new drug shows promising results for those suffering early-stage Alzheimer’s https://www.epmmagazine.com/pharma-manufacturing-news/clinical-trial-suggests-new-drug-may-benefit-early-stage-alz/ https://www.epmmagazine.com/pharma-manufacturing-news/clinical-trial-suggests-new-drug-may-benefit-early-stage-alz/ Thu, 01 Sep 2016 09:11:23 -0000 brain.gif Probiodrug, a biopharmaceutical company developing therapeutic products to treat Alzheimer's disease has entered into a collaboration with Dutch biotech Crossbeta Biosciences https://www.epmmagazine.com/pharma-manufacturing-news/collaboration-key-in-tackling-alzheimers/ https://www.epmmagazine.com/pharma-manufacturing-news/collaboration-key-in-tackling-alzheimers/ Thu, 30 Jun 2016 13:54:00 -0000 alzheimers.jpg Emily Hughes Concert Pharmaceuticals has achieved a $2 million (£1.3m) milestone under its development and license agreement with Avanir Pharmaceuticals for the phase three initiation of AVP-786 for agitation in patients with Alzheimer’s https://www.epmmagazine.com/pharma-manufacturing-news/concert-pharma-achieves-2m-milestone-for-alzheimers-drug/ https://www.epmmagazine.com/pharma-manufacturing-news/concert-pharma-achieves-2m-milestone-for-alzheimers-drug/ Tue, 24 Nov 2015 10:33:00 -0000 alzheimers $2mil.jpg