RSS

Phase III

The Janssen Pharmaceutical Companies of Johnson & Johnson has reported the positive topline results from the ATLAS Phase III study investigating a novel, long acting injectable two-drug regimen for the treatment of HIV-1. more

News

Pfizer and Spark Therapeutics have announced that the Phase III programme for the investigational haemophilia B gene therapy is to be initiated by Pfizer. more

News

Roche has revealed the results of its Phase III CAPSTONE-2 study in which its investigational oral, single-dose antiviral, baloxavir marboxil, has shown superior efficacy in the primary endpoint of time to improvement of flu symptoms versus placebo. more

News

The Independent Data Monitoring Committee (IDMC) has approved the continuation of the Phase III clinical study into OSE Immunotherapeutics’ treatment for Non-Small Cell Lung Cancer (NSCLC) — Tedopi — after immune checkpoint inhibitor treatment. more

News

Swiss-based specialty pharma company, Polyphor, has announced that the first patient has been enrolled in the Phase III clinical trial for murepavadin — a pathogen-specific antibiotic being developed for the treatment of nosocomial pneumonia more

News

Data, recently published in the journal Epilepsia, has demonstrated once-daily monotherapy, Zebinix (esclicarbazeptine acetate), is non-inferior to twice-daily controlled released carbamazepine in the treatment of newly diagnosed focal epilepsy more

News

The European Patent Office has issued a new patent to biotechnology company, CEL-SCI, for its lead investigational immunotherapy, which is undergoing a Phase III clinical trial for head and neck cancer. more

Technology

Axovant Sciences, a clinical-stage biopharmaceutical company, has revealed negative topline results of its Phase III MINDSET trial in Alzheimer’s disease, but the CEO has stressed that the company will continue advancing its pipeline more

News

The Alliance Foundation Trials (AFT) — in conjunction with Pfizer and six international cancer research groups — has launched a randomised open-label Phase III clinical study, PATINA, to evaluate a combination therapy for breast cancer. more

News

Biopharmaceutical company, Ablynx, has announced the completion of patient recruitment for its Phase III HERCULES study of caplacizumab for the treatment of acquired thrombotic thrombocytopenic purpura (aTTP). more

News

RedHill Biopharma has announced dosing of the first patient in the open-label extension study to the Phase III study with RHB-104 for the treatment of Crohn’s disease. more

News

Merck has initiated a global Phase III clinical study of MSB11022, a proposed biosimilar of adalimumab, in chronic plaque psoriasis more

News

Vasopharm has raised £15.3m (€20m) of new capital for Traumatic Brain Injury (TBI) clinical trials more

News

Sanofi and Regeneron Pharmaceuticals have completed enrollment in the global phase three, Odyssey Outcomes trial for patients suffering from acute coronary syndrome (ACS) more

News

The data shows the efficacy and tolerability of flutiform, a combination of fluticasone propionate and formoterol in a single pressurised metered dose inhaler, over 12 weeks in children with asthma aged 5 to <12. more

The trial successfully met its primary efficacy endpoint in demonstrating that BEMA buprenorphine resulted in significantly improved chronic pain relief compared to placebo. more

The Phase III confirmatory trial is referred to as ACT CF (ataluren confirmatory trial in cystic fibrosis) and the primary endpoint is lung function as measured by relative change in percent predicted forced expiratory volume in one second, or FEV1. more

News